b"Medicine & ResearchandamyotrophiclateralsclerosisinolderThis study looked at all CNS-active drugs adults. Analyzing medical claims data fromand their effect on the risk of Alzheimers disease more than 300,000 patients ages 60 and older,by reviewing insurance claims. They found a they found that CNS-active drugs were linkeddecreased risk. The exception was atypical to a reduced risk of AD and all age-relatedantipsychotic drugs. This class of drugs includes neurodegenerative diseases, except for atypicalquetiapine, clozapine, and olanzapine. Given antipsychotics, which increased AD risk.how many people with MS may be on CNS-Combination therapy showed promise, especiallyactive medications, I nd this study reassuring. with certain drug combinations. These ndings could guide precision prevention strategiesNerve stimulation may improve for reducing neurodegenerative disease riskbladder functionin individuals with neuropsychiatric disorders.Researchers in France led a study examining Theresultswerepublishedinthejournalthe effectiveness of transcutaneous tibial Frontiers in Psychiatry.nervestimulationinmanagingoveractive Thrower- People living with MS deal with abladder symptoms in patients with MS. They wide variety of symptoms including fatigue,analyzed data from 82 patients who underwent pain, and mood disorders. Seizures are moretranscutaneous tibial nerve stimulation treatment likely in those living with MS. Many of theseand urodynamic assessments. Results showed issues are treated with CNS-active drugs. Thisimprovements in overactive bladder symptoms list wouldincludegabapentin,pregabalin,based on bladder diaries and the urinary carbamazepine, oxcarbazepine, duloxetine,symptoms profile. However, urodynamic modanil, armodanil, stimulant medications,parameters didn't signicantly change. About and others. Some prior studies have suggested42.5 percent of patients reported good response an increased risk for dementia with the long-termtotreatment.Highurgencyto voidbefore use of gabapentin and pregabalin. These studiestreatment correlated with higher satisfaction. did not consider underlying diseases that mayThe study suggests transcutaneous tibial nerve have led to the use of gabapentin or pregabalin.stimulation can help alleviate overactive For instance, someone may be using gabapentinbladder symptoms in patients with MS, for a painful diabetic neuropathy. Diabetesespecially in those with high urgency levels. itself is linked to a higher risk for AlzheimersThendings werepublishedintheWorld disease.Journal of Urology COOLING VESTSThrower- Bladder issues are common for those living with MS and can greatly affect YOU WANTquality of life. The bladder can be affected TO WEAR. several ways by MS. People may experience a small overactive bladder with symptoms such as urinary frequency, urgency, and incontinence. Nighttime urinary frequency may interrupt sleep and contribute to daytime fatigue. MSF cooling program supplier MS can also cause a large, underactive 855-232-7233 bladder. This is sometimes referred to as a msfocusmagazine.org 50"