20 msfocusmagazine.org seems to work best in the younger patient with an aggressive relapsing form of MS, with less impressive results in progressive forms of MS. Earlier, we discussed the transition from relapsing-remitting to secondary progressive. Given that this transition is not always black and white, the use of any therapy approved for relapsing forms of MS may be discussed in secondary progressive forms. For people with MS who are already on treatment, the question sometimes arises, "How do I know if I have moved into secondary progressive?" Many people with MS still see some slow progression of disability in spite of treatment. This presents a difficult situation. It could be that their treatment is preventing relapses and new lesions, completely stopping the progression of disability. Stopping treatment may then allow for relapses and new MRI lesions to occur. Unless a better treatment option is available in these cases, it may be safest to continue with a therapy. Turning back the clock Mesenchymal stem cells, clemastine, and anti-lingo are all currently being researched as options for turning back the clock and repairing damage caused by MS. Research continues to move forward towards a day when we can hopefully reverse disability. How have you adapted to increasing MS symptoms? Shanyn Sisnroy Krieger: As my symptoms increase, I just have to keep a positive mind and lifestyle. I know this disease will never get better, only worse, and there is not much I can do. I just swallow my pride and tell myself that "Yes, using the cart at Wal-Mart is embarrassing, but falling is worse!" I just have to take things as they come. Adapt and overcome! Erik Nelson Sisnroy: I have adapted by changing my lifestyle: a healthy lifestyle, good support system, and the word of God. That’s how I adapt. I try to make healthy lifestyle changes with exercising, dieting and my faith in God. Dennis Tooley: I recognize the cognitive issues that I have because of the MS. I have had to rely heavily on technology to help keep my memory intact. I rely very heavily on my smartphone for reminders. I make notes that help me remember what I'm supposed to buy. I make calendar reminders that have alarms to remind me of appointments. I take pictures more now with my phone camera so that I can remember certain events. I’m a comic and I use the voice recorder on my phone to record my comedy shows so I can go back and remember what went really well and what I need to work on before my next show. Having the technology all in one area, in my phone, makes it convenient for me to have all of these aids in one place. Mark Brannan: Replace your depression with laughter and smiles. Love yourself like you never have. Lean on your friends with MS. One by one, I have overcome and adapted to my symptoms. I am in a power chair with the use of only one arm. Have faith. Medicine & Research