b'How should I use KESIMPTA?The most common side effects of KESIMPTA include:See the detailed Instructions for Use that comes with upper respiratory tract infection, with symptoms such asKESIMPTA for information about how to prepare andsore throat and runny nose, and headache. (See Whatinject a dose of KESIMPTA and how to properly throwis the most important information I should know aboutaway (dispose of) used KESIMPTA Sensoready pens orKESIMPTA?)prefilled syringes.headacheUse KESIMPTA exactly as your healthcare provider tells These are not all the possible side effects of KESIMPTA.you to use it. Call your doctor for medical advice about side effects. KESIMPTA is given as an injection under your skin You may report side effects to FDA at 1-800-FDA-1088. (subcutaneous injection), in your thigh or stomach-area(abdomen) by you or a caregiver. A caregiver may also How should I store KESIMPTA?give you an injection of KESIMPTA in your upper outerStore KESIMPTA in a refrigerator between 36F to 46Farm. (2C to 8C).Your healthcare provider will show you how to prepareKeep KESIMPTA in the original carton until ready for useand inject KESIMPTA the right way before you use it for to protect from light.the first time.If needed, KESIMPTA may be stored for up to 7 days atroom temperature, up to 86F (30C).Do not inject into areas where the skin is tender, bruised,red, scaly or hard. Avoid areas with moles, scars orstretch marks. Write the date taken out of the refrigerator in the space The initial dosing is 20 mg of KESIMPTA given by provided on the carton. subcutaneous injection at Weeks 0, 1, and 2. There is no I f stored below 86F (30C), unused KESIMPTA may beinjection at Week 3. Starting at Week 4 and then every returned to the refrigerator and must be used within themonth, the recommended dose is 20 mg of KESIMPTA next 7 days. If this KESIMPTA is not used within those 7administered by subcutaneous injection. days, then discard the medicine.If you miss an injection of KESIMPTA at Week 0, 1, or 2, talkDo not freeze KESIMPTA.to your healthcare provider. If you miss a monthly injection,Do not shake KESIMPTA.give it as soon as possible without waiting until the nextKeep KESIMPTA and all medicines out of the reach of scheduled dose. After that, give your KESIMPTA injections achildren. month apart.What are the possible side effects of KESIMPTA? General information about the safe and effective use of KESIMPTA.KESIMPTA may cause serious side effects, including:Medicines are sometimes prescribed for purposes other See What is the most important information I shouldthan those listed in a Medication Guide. Do not use know about KESIMPTA? KESIMPTA for a condition for which it was not prescribed. Do not give KESIMPTA to other people, even if they have Injection-related reactions. Injection-related reactions isa common side effect of KESIMPTA. Injecting KESIMPTA the same symptoms that you have. It may harm them.can cause injection-related reactions that can happen You can ask your pharmacist or healthcare provider for within 24 hours (1 day) following the first injections and information about KESIMPTA that is written for health with later injections. Talk with your healthcare provider if professionals.you have any of these signs and symptoms: What are the ingredients in KESIMPTA?o at or near the injection site: redness of the skin,Active ingredient: ofatumumabswelling, itching and pain oro that may happen when certain substances are Inactive ingredients: Sensoready pen and prefilled syringe: arginine, disodium edetate, polysorbate 80, released in your body: fever, headache, pain in the sodium acetate trihydrate, sodium chloride, and Water for muscles, chills, and tiredness. Injection. Hydrochloric acid may be added. Low immunoglobulins. KESIMPTA may cause a decrease in some types of antibodies. Your healthcareprovider will do blood tests to check your bloodimmunoglobulin levels.10/22 24215812060005_KSM_DTC_JLS_MS_Focus_M3FR.indd 2 12/13/23 11:26 AM'