b'Important Safety Information (cont)Are pregnant, think that you might be pregnant, or plan to become pregnant. It is not known if What is the most important information I shouldKESIMPTA will harm your unborn baby. Females know about KESIMPTA? who can become pregnant should use birth control KESIMPTA can cause serious side effects such as: (contraception) during treatment with KESIMPTA andInfections. Serious infections can happen duringfor 6 months after your last treatment. Talk with your treatment with KESIMPTA. If you have an activeHCP about what birth control method is right for you Speak up about infection, your healthcare provider (HCP) shouldduring this time.delay your treatment with KESIMPTA until your Are breastfeeding or plan to breastfeed. It is not infection is gone. KESIMPTA taken before or afterknown if KESIMPTA passes into your breast milk. Talkwhat you need.other medicines that weaken the immune systemto your HCP about the best way to feed your baby if may increase your risk of getting infections. Tell youryou take KESIMPTA.HCP right away if you have any infections or get anyTell your HCP about all the medicines you take, symptoms including painful and frequent urination,including prescription and over-the-counter medicines, nasal congestion, runny nose, sore throat, fever, chills,vitamins, and herbal supplements.cough, or body aches. HBV reactivation. If you have ever had HBV infection,How should I use KESIMPTA? it may become active again during or after treatmentSee the detailed Instructions for Use that comes with with KESIMPTA (reactivation). If this happens, it mayKESIMPTA for information about how to prepare and cause serious liver problems including liver failure orinject a dose of KESIMPTA and how to properly throw death. Before starting KESIMPTA, your HCP will do aaway (dispose of) used KESIMPTA Sensoready pens blood test to check for HBV. They will also continueor prefilled syringes.to monitor you during and after treatment with Use KESIMPTA exactly as your HCP tells you to KESIMPTA for HBV. Tell your HCP right away if youuse it. get worsening tiredness or yellowing of your skin or Your HCP will show you how to prepare and inject the white part of your eyes. KESIMPTA the right way before you use it for the firstProgressive Multifocal Leukoencephalopathy (PML). time.PML may happen with KESIMPTA. PML is a rare, Do not inject into areas where the skin is tender, serious brain infection caused by a virus that may getbruised, red, scaly or hard. Avoid areas with moles, worse over days or weeks. PML can result in death orscars, or stretch marks.severe disability. Tell your HCP right away if you have any new or worsening neurologic signs or symptoms.KESIMPTA may cause serious side effects including:These may include weakness on one side of your Injection-related reactions. Injection-related body, loss of coordination in arms and legs, visionreactions are a common side effect of KESIMPTA. problems, changes in thinking and memory, whichInjecting KESIMPTA can cause injection-related may lead to confusion and personality changes.reactions that can happen within 24 hours (1 day)Weakened immune system. KESIMPTA taken beforefollowing the first injections and with later injections. or after other medicines that weaken the immuneTalk with your HCP if you have any of these signs and system could increase your risk of getting infections. symptoms:Before you take KESIMPTA, tell your HCP about all at or near the injection site: redness of the skin, your medical conditions, including if you: swelling, itching, and pain orHave or think you have an infection including HBV that may happen when certain substances are or PML. released in your body: fever, headache, pain in theHave ever taken, currently take, or plan to takemuscles, chills, and tiredness.medicines that affect your immune system. These Low immunoglobulins. KESIMPTA may cause a medicines could increase your risk of getting andecrease in some types of antibodies. Your HCP infection. will do blood tests to check your bloodHave had a recent vaccination or are scheduled toimmunoglobulin levels.receive any vaccinations. The most common side effects of KESIMPTA include: You should receive any required live or live-Upper respiratory tract infection, with symptoms such attenuated vaccines at least 4 weeks before youas sore throat and runny nose, and headache.start treatment with KESIMPTA. You should not Headache.receive live or live-attenuated vaccines whileYou are encouraged to report negative side effects you are being treated with KESIMPTA and untilof prescription drugs to the FDA. Visit www.fda.gov/your HCP tells you that your immune system is nomedwatch, or call 1-800-FDA-1088. longer weakened. Whenever possible, you should receive any non-livePlease see accompanying Consumer Brief Summary vaccines at least 2 weeks before you start treatmenton the following page.with KESIMPTA.Talk to your HCP about vaccinations for your baby if you used KESIMPTA during your pregnancy.11969197_Kesimpta_DTC_JLS_Ad_MS_Focus_M5FR.indd 1 8/24/23 4:09 PM'