b'medicines, vitamins, and herbal supplements. a decrease in some types of antibodies. Your Know the medicines you take. Keep a list of them tohealthcare provider will do blood tests to checkshow your healthcare provider and pharmacist whenyour blood immunoglobulin levels.you get a new medicine. The most common side effects of KESIMPTA include:How should I use KESIMPTA?upper respiratory tract infection, with symptomsSee the detailed Instructions for Use that comessuch as sore throat and runny nose, and headache. with KESIMPTA for information about how to(See What is the most important information I prepare and inject a dose of KESIMPTA and how toshould know about KESIMPTA?)properly throw away (dispose of) used KESIMPTAheadacheSensoready pens or prefilled syringes. These are not all the possible side effects of Use KESIMPTA exactly as your healthcare providerKESIMPTA. Call your doctor for medical advice abouttells you to use it.side effects. KESIMPTA is given as an injection under your skinYou may report side effects to FDA at 1-800-FDA-1088. (subcutaneous injection), in your thigh or stomach- How should I store KESIMPTA?area (abdomen) by you or a caregiver. A caregiver may also give you an injection of KESIMPTA in your Store KESIMPTA in a refrigerator between 36F to upper outer arm. 46F (2C to 8C). Keep KESIMPTA in the original carton until ready forYour healthcare provider will show you how to prepare and inject KESIMPTA the right way beforeuse to protect from light.you use it for the first time. If needed, KESIMPTA may be stored for up to Do not inject into areas where the skin is tender,7 days at room temperature, up to 86F (30C). bruised, red, scaly or hard. Avoid areas with moles, Write the date taken out of the refrigerator in the scars or stretch marks. space provided on the carton.The initial dosing is 20 mg of KESIMPTA given byIf stored below 86F (30C), unused KESIMPTA maysubcutaneous injection at Weeks 0, 1, and 2. There isbe returned to the refrigerator and must be used no injection at Week 3. Starting at Week 4 and thenwithin the next 7 days. If this KESIMPTA is not used every month, the recommended dose is 20 mg ofwithin those 7 days, then discard the medicine. KESIMPTA administered by subcutaneous injection. Do not freeze KESIMPTA.If you miss an injection of KESIMPTA at Week 0, 1, or 2,Do not shake KESIMPTA.talk to your healthcare provider. If you miss a monthlyKeep KESIMPTA and all medicines out of the reach injection, give it as soon as possible without waitingof children. until the next scheduled dose. After that, give your KESIMPTA injections a month apart. General information about the safe and effective What are the possible side effects of KESIMPTA? use of KESIMPTA.KESIMPTA may cause serious side effects, including:Medicines are sometimes prescribed for purposes See What is the most important information Iother than those listed in a Medication Guide. Do not should know about KESIMPTA? use KESIMPTA for a condition for which it was not prescribed. Do not give KESIMPTA to other people, Injection-related reactions. Injection-relatedeven if they have the same symptoms that you have.reactions is a common side effect of KESIMPTA.It may harm them.Injecting KESIMPTA can cause injection-relatedYou can ask your pharmacist or healthcare provider reactions that can happen within 24 hours (1 day)for information about KESIMPTA that is written for following the first injections and with later injections.health professionals.Talk with your healthcare provider if you have any ofWhat are the ingredients in KESIMPTA?these signs and symptoms:oat or near the injection site: redness of the skin,Active ingredient: ofatumumabswelling, itching and pain orInactive ingredients: Sensoready pen and prefilled othat may happen when certain substances aresyringe: arginine, disodium edetate, polysorbate 80, released in your body: fever, headache, pain insodium acetate trihydrate, sodium chloride, and Water the muscles, chills, and tiredness. for Injection. Hydrochloric acid may be added.Low immunoglobulins. KESIMPTA may cause10/22 24215811969197_Kesimpta_DTC_JLS_Ad_MS_Focus_M5FR.indd 2 8/24/23 4:09 PM'