b'Important Safety Information (cont) your baby if you used KESIMPTA during your pregnancy.What is the most important information I should know Are pregnant, think that you might be pregnant, or about KESIMPTA? plan to become pregnant. It is not known if KESIMPTA KESIMPTA can cause serious side effects such as: will harm your unborn baby. Females who can becomeInfections. Serious infections can happen duringpregnant should use birth control (contraception) during treatment with KESIMPTA. If you have an activetreatment with KESIMPTA and for 6 months after your infection, your healthcare provider (HCP) should delaylast treatment. Talk with your HCP about what birth your treatment with KESIMPTA until your infection iscontrol method is right for you during this time.gone. KESIMPTA taken before or after other medicines Are breastfeeding or plan to breastfeed. It is not known that weaken the immune system may increase yourif KESIMPTA passes into your breast milk. Talk to your risk of getting infections. Tell your HCP right away ifHCP about the best way to feed your baby if you take you have any infections or get any symptoms includingKESIMPTA.painful and frequent urination, nasal congestion, runnyTell your HCP about all the medicines you take, nose, sore throat, fever, chills, cough, or body aches. including prescription and over-the-counter medicines,HBV reactivation. If you have ever had HBV infection, itvitamins, and herbal supplements.may become active again during or after treatment with KESIMPTA (reactivation). If this happens, it may causeHow should I use KESIMPTA? serious liver problems including liver failure or death.See the detailed Instructions for Use that comes with Before starting KESIMPTA, your HCP will do a blood testKESIMPTA for information about how to prepare and to check for HBV. They will also continue to monitor you inject a dose of KESIMPTA and how to properly throw during and after treatment with KESIMPTA for HBV. Tellaway (dispose of) used KESIMPTA Sensoready pens or your HCP right away if you get worsening tiredness orprefilled syringes.yellowing of your skin or the white part of your eyes.Use KESIMPTA exactly as your HCP tells you toProgressive Multifocal Leukoencephalopathy (PML). use it. PML may happen with KESIMPTA. PML is a rare, serious Your HCP will show you how to prepare and inject brain infection caused by a virus that may get worseKESIMPTA the right way before you use it for the over days or weeks. PML can result in death or severefirst time.disability. Tell your HCP right away if you have any Do not inject into areas where the skin is tender, new or worsening neurologic signs or symptoms. Thesebruised, red, scaly or hard. Avoid areas with moles, may include weakness on one side of your body, loss ofscars, or stretch marks.coordination in arms and legs, vision problems, changes in thinking and memory, which may lead to confusionKESIMPTA may cause serious side effects including:and personality changes. Injection-related reactions. Injection-related reactionsWeakened immune system. KESIMPTA taken before orare a common side effect of KESIMPTA. Injecting after other medicines that weaken the immune systemKESIMPTA can cause injection-related reactions that could increase your risk of getting infections. can happen within 24 hours (1 day) following the first injections and with later injections. Talk with your HCP if Before you take KESIMPTA, tell your HCP about all youryou have any of these signs and symptoms:medical conditions, including if you:at or near the injection site: redness of the skin,Have or think you have an infection including HBVswelling, itching, and pain oror PML.that may happen when certain substances areHave ever taken, currently take, or plan to takereleased in your body: fever, headache, pain in the medicines that affect your immune system. Thesemuscles, chills, and tiredness.medicines could increase your risk of getting Low immunoglobulins. KESIMPTA may cause a an infection. decrease in some types of antibodies. Your HCPHave had a recent vaccination or are scheduled towill do blood tests to check your blood immunoglobulin receive any vaccinations. levels. You should receive any required live or live-attenuated vaccines at least 4 weeks before youThe most common side effects of KESIMPTA include:start treatment with KESIMPTA. You should not Upper respiratory tract infection, with symptoms such receive live or live-attenuated vaccines while youas sore throat and runny nose, and headache.are being treated with KESIMPTA and until your Headache.HCP tells you that your immune system is no longerYou are encouraged to report negative side effects weakened. of prescription drugs to the FDA. Visit www.fda.gov/ Whenever possible, you should receive any non- medwatch, or call 1-800-FDA-1088. live vaccines at least 2 weeks before you start treatment with KESIMPTA.Please see accompanying Consumer Brief Summary onTalk to your HCP about vaccinations forthe following page.11900221_KSM_DTC_Momentum_Print_M3FR.indd 1 2/1/23 1:04 PM'