b'Consumer Brief SummaryThe risk information provided here is not comprehensive.clinically isolated syndrome This information does not take the place of talking withrelapsing-remitting diseaseyour doctor about your medical condition or treatment. active secondary progressive diseaseTo learn more about KESIMPTA (ofatumumab) injections, talk to your doctor or pharmacist. For more informationIt is not known if KESIMPTA is safe or effective in children.and to obtain the FDA-approved product labeling, callDo not use KESIMPTA if you:1-888-669-6682 or visit www.kesimpta.com. have active hepatitis B virus infection.What is the most important information I should knowBefore using KESIMPTA, tell your healthcare provider about KESIMPTA? about all of your medical conditions, including if you:KESIMPTA can cause serious side effects, including: have or think you have an infection, including HBV orInfections. Serious infections can happen during PML. See What is the most important information I treatment with KESIMPTA. If you have an active infection,should know about KESIMPTA?your healthcare provider should delay your treatment withhave ever taken, currently take, or plan to take KESIMPTA until your infection is gone. KESIMPTA taken before or after other medicines that weaken the immunemedicines that affect your immune system. These system may increase your risk of getting infections.medicines could increase your risk of getting an infection.Tell your healthcare provider right away if you have anyhave had a recent vaccination or are scheduled to infections or get any symptoms including painful and frequent urination, nasal congestion, runny nose, sorereceive any vaccinations.throat, fever, chills, cough, or body aches.oYou should receive any required live or live-Hepatitis B virus (HBV) reactivation. Before startingattenuated vaccines at least 4 weeks before you start treatment with KESIMPTA. You should not treatment with KESIMPTA, your healthcare provider willreceive live or live-attenuated vaccines while you do blood tests to check for HBV. If you have ever hadare being treated with KESIMPTA and until your HBV infection, the HBV may become active again duringhealthcare provider tells you that your immune system or after treatment with KESIMPTA. Hepatitis B virusis no longer weakened.becoming active again (called reactivation) may causeoWhenever possible, you should receive any non-live serious liver problems including liver failure or death. You should not receive KESIMPTA if you have active hepatitisvaccines at least 2 weeks before you start treatment B liver disease. Your healthcare provider will monitorwith KESIMPTA. you for HBV infection during and after you stop usingoTalk to your healthcare provider about vaccinations KESIMPTA. Tell your healthcare provider right away iffor your baby if you used KESIMPTA during your you get worsening tiredness or yellowing of your skin orpregnancy.white part of your eyes during treatment with KESIMPTA. are pregnant, think that you might be pregnant, or planProgressive Multifocal Leukoencephalopathy (PML).to become pregnant. It is not known if KESIMPTA willPML may happen with KESIMPTA. PML is a rare, seriousharm your unborn baby. Females who can become brain infection caused by a virus that may get worsepregnant should use birth control (contraception) during over days or weeks. PML can result in death or severetreatment with KESIMPTA and for 6 months after yourdisability. Tell your healthcare provider right away iflast treatment. Talk with your healthcare provider about you have any new or worsening neurologic signs orwhat birth control method is right for you during this time.symptoms. These may include weakness on one side of your body, loss of coordination in arms and legs, visionare breastfeeding or plan to breastfeed. It is not knownproblems, changes in thinking and memory which mayif KESIMPTA passes into your breast milk. Talk to your lead to confusion and personality changes. healthcare provider about the best way to feed your baby if you take KESIMPTA.Weakened immune system. KESIMPTA taken before orTell your healthcare provider about all the medicines after other medicines that weaken the immune systemyou take, including prescription and over-the-counter could increase your risk of getting infections. medicines, vitamins, and herbal supplements.What is KESIMPTA? Know the medicines you take. Keep a list of them to show KESIMPTA is a prescription medicine used to treat adultsyour healthcare provider and pharmacist when you get a with relapsing forms of multiple sclerosis (MS) including: new medicine.11900221_KSM_DTC_Momentum_Print_M3FR.indd 2 2/1/23 1:04 PM'